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Stx1B

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For Research Use Only. Not For Clinical Use.


Background

The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
Protein class

Disease related genes, Human disease related genes

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Horizontal cells, Excitatory neurons, Inhibitory neurons, Late spermatids)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced

Interaction

Interacts with OTOF. Interacts with SYT6 and SYT8; the interaction is Ca(2+)-dependent (By similarity).

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