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TAL1
TAL1 (MALAT1 Antisense Transcript) is an RNA Gene, and is affiliated with the ncRNA class.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Erythroid cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HEL, HMC-1, HUVEC TERT2, JURKAT, K-562, MOLT-4, TIME)
Interaction
Efficient DNA binding requires dimerization with another bHLH protein. Forms heterodimers with TCF3. Binds to the LIM domain containing protein LMO2 and to DRG1. Can assemble in a complex with LDB1 and LMO2. Component of a TAL-1 complex composed at least of CBFA2T3, LDB1, TAL1 and TCF3. Interacts with SBNO2; this interaction inhibits TAL1 occupancy of the DCSTAMP promoter, leading to the activation of the DCSTAMP promoter by the transcription factor MITF.
Molecular function
Developmental protein, DNA-binding
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, IP, IF, ELISA
- Mouse Anti-TAL1 Recombinant Antibody (clone 4G1) (VS3-XY1484)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IP, IF
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For Research Use Only. Not For Clinical Use.