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Target
Kallikrein 3 (1)KLK3 (59)KLK3 (Kallikrein Related Peptidase 3) (1)Prostate specific antigen (PSA) (2)PSA (1)
Application
Antigen-Sweeping In Vivo. (1)Biosensors (1)Dot (1)ELISA (27)FC (10)FCM (34)FuncS (15)ICC (6)IF (8)IHC (21)IHC-Fr (4)IHC-P (13)MHC Multimer (2)N/A (2)Neut (6)WB (27)
Host
Type
ADCC enhanced antibody (1)Antibody (1)Chicken antibody (2)Dromedary VHH (3)Fab (2)Human IgG1 (1)Human scFv (1)Humanized Fab (1)Humanized IgG1, κ (1)IgG (3)IgG2 (2)IgG2b (1)Llama VHH (1)Mouse Fab (4)Mouse IgG (12)Mouse IgG1 (9)Mouse IgG1, κ (1)Mouse IgM (1)Mouse scFv (4)Rabbit IgG (5)scFv (2)
Species Reactivity
Expression Host
CHO (3)CHO/HEK293/E. coli (3)E. coli (3)Fucosyltransferse-engineered cell line (1)HEK 293 (1)HEK-293 (1)See the COA (16)
Conjugate
APC (6)Biotin (2)BV421 (1)FITC (2)PE (19)Uconjugated (1)Unconjugated (25)Unlabeled, Biotin, R-PE, APC (3)
Derivation
Human (3)Humanized (3)Mouse (11)Mouse phage display scFv library (3)Phage Display Library (3)Phage display library screening (1)
Classification
Allele
A*02:01 (11)A*02:07 (1)A*0201 (1)A*11:01 (1)A*24:02 (4)A*31:01 (1)A*33:01 (1)A*68:01 (1)B*07:02 (1)B*35:01 (2)B*51:01 (2)B*53:01 (1)H-2Db (3)H2-Db (2)H-2Ld (4)
Class
Antigen
Antigen Species
Antibody Type
TDG
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Anti-TDG Products
- Mouse Anti-TDG Recombinant Antibody (clone 35G8) (MOB-3562z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
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- Anti-Human TDG Immunohistochemistry Kit (VS-0525-XY7154)
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- Species Reactivity: Human
- Target: TDG
- Application: IHC
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- Anti-Mouse TDG Immunohistochemistry Kit (VS-0525-XY7155)
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- Species Reactivity: Human, Mouse, Rat, Bovine, Chicken, Frog
- Target: TDG
- Application: IHC
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- Anti-TDG Immunohistochemistry Kit (VS-0325-XY2263)
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- Species Reactivity: Human, Mouse, Rat
- Target: TDG
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.
Protein class
Enzymes
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer. Interacts with AICDA and GADD45A.
Molecular function
Activator, Chromatin regulator, Hydrolase
More Types Infomation