TFEB

AbPlus Formats

Anti-TFEB Recombinant Antibody Products

Anti-TFEB Immunohistochemistry Kit (VS-0325-XY2274)
- Species Reactivity: Human, Mouse, Rat
- Target: TFEB
- Application: IHC
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For Research Use Only. Not For Clinical Use.

TFEB (Transcription Factor EB) is a Protein Coding gene. Diseases associated with TFEB include Renal Cell Carcinoma, Xp11-Associated and Microphthalmia. Among its related pathways are Mitophagy - animal and PI3K-AKT-mTOR signaling pathway and therapeutic opportunities. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and protein dimerization activity. An important paralog of this gene is MITF.

Protein class

Cancer-related genes, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Syncytiotrophoblasts, Oligodendrocytes)

Immune cell specificity

Group enriched (neutrophil, memory B-cell, naive B-cell, eosinophil, intermediate monocyte, classical monocyte, myeloid DC, non-classical monocyte)

Cell line specificity

Cell line enhanced (BEWO, Daudi, OE19, U-698)

Interaction

Homodimer and heterodimer; with TFE3 or MITF.

Molecular function

Activator, DNA-binding

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