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TUBB4A
Loading...Anti-TUBB4A Products
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- Class: Class I
- Antigen: Tubulin beta 4
- Antigen Species: Human
- Peptide: FLALIICNA
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Mouse Anti-NHP TUBB4A Recombinant Antibody (clone OTI3F1) (VS-1024-XY52)
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- Species Reactivity: Human, Mouse, Non-human primate, Rat
- Type: Mouse IgG2a
- Application: WB, IHC, FC
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- Anti-Mouse TUBB4A Immunohistochemistry Kit (VS-0525-XY7630)
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- Species Reactivity: Human, Mouse, Rat
- Target: TUBB4A
- Application: IHC
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- Anti-TUBB4A Immunohistochemistry Kit (VS-0525-XY7629)
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- Species Reactivity: Human
- Target: TUBB4A
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the beta tubulin family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene cause hypomyelinating leukodystrophy-6 and autosomal dominant torsion dystonia-4. Alternate splicing results in multiple transcript variants encoding different isoforms. A pseudogene of this gene is found on chromosome X.
Protein class
Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Oligodendrocytes, Theca cells, Muller glia cells, Excitatory neurons)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (AN3-CA, HAP1, HEL, PC-3, REH, SH-SY5Y)
Interaction
Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
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