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TUFT1
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For Research Use Only. Not For Clinical Use.
Background
Tuftelin is an acidic protein that is thought to play a role in dental enamel mineralization and is implicated in caries susceptibility. It is also thought to be involved with adaptation to hypoxia, mesenchymal stem cell function, and neurotrophin nerve growth factor mediated neuronal differentiation.
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Glandular and luminal cells, Basal keratinocytes, Suprabasal keratinocytes)
Immune cell specificity
Immune cell enhanced (basophil)
Cell line specificity
Low cell line specificity
Interaction
Interacts with TFIP11.
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