+ Filter
Loading...
TWIST2
Anti-TWIST2 Recombinant Antibody Products
- Mouse Anti-TWIST2 Recombinant Antibody (clone 1A11D9) (VS7-0425-WR1074)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA
Compare
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found. [provided by RefSeq, Apr 2014]
Protein class
Disease related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Endometrial stromal cells, Fibroblasts, Leydig cells, Peritubular cells, Theca cells)
Immune cell specificity
Immune cell enriched (eosinophil)
Cell line specificity
Cell line enhanced (ASC diff, ASC TERT1, BJ, BJ hTERT+, fHDF/TERT166, U-2197)
Interaction
Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with TCF3/E12. Also interacts with MEF2C (By similarity).
Molecular function
Developmental protein, DNA-binding, Repressor
More Types Infomation