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Tofacitinib
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- Mouse Anti-Tofacitinib Recombinant Antibody (clone 10A6.C5) (HPAB-AP473-YC)
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- Type: Mouse IgG
- Application: ELISA
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- Mouse Anti-Tofacitinib Recombinant Antibody (clone 10F10.H5) (HPAB-AP474-YC)
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- Type: Mouse IgG
- Application: ELISA
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- Mouse Anti-Tofacitinib Recombinant Antibody (clone 12D4.G6) (HPAB-AP475-YC)
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- Type: Mouse IgG
- Application: ELISA
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- Mouse Anti-Tofacitinib Recombinant Antibody (clone 12H4.G2) (HPAB-AP476-YC)
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- Type: Mouse IgG
- Application: ELISA
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- Mouse Anti-Tofacitinib Recombinant Antibody (clone 5A3.E5) (HPAB-AP477-YC)
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- Type: Mouse IgG
- Application: ELISA
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- Mouse Anti-Tofacitinib Recombinant Antibody (clone 6D9.A5) (HPAB-AP478-YC)
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- Type: Mouse IgG
- Application: ELISA
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- Recombinant Anti-Tofacitinib Antibody (MOB-991)
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- Derivation: Mouse
- Type: IgG
- Application: WB, IP, FuncS
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- Recombinant Anti-Tofacitinib Antibody Fab Fragment (MOB-991-F(E))
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- Derivation: Mouse
- Type: Fab
- Application: WB, IF, FuncS
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- Recombinant Anti-Tofacitinib Antibody scFv Fragment (MOB-991-S(P))
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- Derivation: Mouse
- Type: scFv
- Application: Neut, IF, FuncS
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- Recombinant Human Anti-Tofacitinib Antibody Fab Fragment (MHH-991-F(E))
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- Derivation: Human
- Type: Fab
- Application: IP, IF, Biosensors, FuncS
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- Recombinant Human Anti-Tofacitinib Antibody scFv Fragment (MHH-991-S(P))
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- Derivation: Human
- Type: scFv
- Application: FC, IP, FuncS
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- Mouse Anti-Tofacitinib Recombinant Antibody (clone 10A6.C5); Fab Fragment (HPAB-AP473-YC-F(E))
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- Type: Mouse Fab
- Application: ELISA
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- Mouse Anti-Tofacitinib Recombinant Antibody (clone 10F10.H5); Fab Fragment (HPAB-AP474-YC-F(E))
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- Type: Mouse Fab
- Application: ELISA
Compare
- Mouse Anti-Tofacitinib Recombinant Antibody (clone 12D4.G6); Fab Fragment (HPAB-AP475-YC-F(E))
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- Type: Mouse Fab
- Application: ELISA
Compare
- Mouse Anti-Tofacitinib Recombinant Antibody (clone 12H4.G2); Fab Fragment (HPAB-AP476-YC-F(E))
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- Type: Mouse Fab
- Application: ELISA
Compare
- Mouse Anti-Tofacitinib Recombinant Antibody (clone 5A3.E5); Fab Fragment (HPAB-AP477-YC-F(E))
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- Type: Mouse Fab
- Application: ELISA
Compare
- Mouse Anti-Tofacitinib Recombinant Antibody (clone 6D9.A5); Fab Fragment (HPAB-AP478-YC-F(E))
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- Type: Mouse Fab
- Application: ELISA
Compare
- Mouse Anti-Tofacitinib Recombinant Antibody (clone 10A6.C5); scFv Fragment (HPAB-AP473-YC-S(P))
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- Type: Mouse scFv
- Application: ELISA
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- Mouse Anti-Tofacitinib Recombinant Antibody (clone 10F10.H5); scFv Fragment (HPAB-AP474-YC-S(P))
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- Type: Mouse scFv
- Application: ELISA
Compare
- Mouse Anti-Tofacitinib Recombinant Antibody (clone 12D4.G6); scFv Fragment (HPAB-AP475-YC-S(P))
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- Type: Mouse scFv
- Application: ELISA
Compare
- Mouse Anti-Tofacitinib Recombinant Antibody (clone 12H4.G2); scFv Fragment (HPAB-AP476-YC-S(P))
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- Type: Mouse scFv
- Application: ELISA
Compare
- Mouse Anti-Tofacitinib Recombinant Antibody (clone 5A3.E5); scFv Fragment (HPAB-AP477-YC-S(P))
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- Type: Mouse scFv
- Application: ELISA
Compare
- Mouse Anti-Tofacitinib Recombinant Antibody (clone 6D9.A5); scFv Fragment (HPAB-AP478-YC-S(P))
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- Type: Mouse scFv
- Application: ELISA
Compare
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For Research Use Only. Not For Clinical Use.
Background
Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate. Besides rheumatoid arthritis, tofacitinib has also been studied in clinical trials for the prevention of organ transplant rejection, and is currently under investigation for the treatment of psoriasis. Known adverse effects include nausea and headache as well as more serious immunologic and hematological adverse effects. Tofacitinib is marketed under the brand name Xeljanz by Pfizer.