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Trans pT231-MAPT

Anti-Trans pT231-MAPT Products

Mouse Anti-Trans pT231-MAPT Recombinant Antibody (HPAB-0498-YJ) (HPAB-0498-YJ)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, IHC, Neut, FuncS
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Mouse Anti-Trans pT231-MAPT Recombinant Antibody; scFv Fragment (HPAB-0498-YJ-S(P)) (HPAB-0498-YJ-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, IHC, Neut, FuncS
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Mouse Anti-Trans pT231-MAPT Recombinant Antibody; Fab Fragment (HPAB-0498-YJ-F(E)) (HPAB-0498-YJ-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, IHC, Neut, FuncS
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For Research Use Only. Not For Clinical Use.

Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.