VLPs

Virus-likeparticles (VLPs) are the shell structures without virus nucleic acid. Many virus structural proteins have the ability to automatically assemble into VLPs, which are similar to natural virus particles in morphological structure and have strong immunogenicity and biological activity. Because VLPs do not contain viral genetic material, they are not infectious, and some of them have been successfully used in clinical applications as vaccines. VLPs structurally allow the insertion of exogenous genes or gene fragments to form chimeric VLPs and display exogenous antigens on its surface. In addition, most viral VLPs have the ability to encapsulate nucleic acids or other small molecules that can be used as genes or drugsThe vehicle of the object.