Recombinant Mouse Anti-CHIKV VLP Antibody (m10) (CAT#: PABL-044)
Recombinant Mouse Antibody (m10) is capable of binding to CHIKV VLP, expressed in Chinese Hamster Ovary cells (CHO). This antibody could stabilize the viral surface, hindering the exposure of the fusion-loop, likely neutralizing infection by blocking fusion.
Specific Inquiry
Inhib
Figure 1 Inhibition of CHIKV by IgG and Fab fragments.
Neutralizing activity of intact MAb and Fab fragments against CHIKV is shown for m10, as determined by the reduction in the number of focus-forming units (FFU) on Vero cells.
Sun, S., Xiang, Y., Akahata, W., Holdaway, H., Pal, P., Zhang, X., ... & Rossmann, M. G. (2013). Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization. Elife, 2, e00435.
Specifications
- Immunogen
- Chikungunya virus Chikungunya virus-like particles
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native CHIKV VLPs
- Species Reactivity
- CHIKV
- Clone
- m10
- Applications
- Inhib
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- This antibody has been reported for use in Inhibition.
Target
- Alternative Names
- VLPs; Chikungunya virus-like particles; CHIKV; Chikungunya virus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-042 | Recombinant Mouse Anti-CHIKV VLP Antibody (9.8B) | WB, ELISA, FuncS | IgG |
| PABL-043 | Recombinant Mouse Anti-CHIKV VLP Antibody (CHK152) | IHC, Neut, Inhib, FuncS | IgG |
| PABL-045 | Recombinant Mouse Anti-CHIKV VLP Antibody (m242) | Inhib | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-042 | Recombinant Mouse Anti-CHIKV VLP Antibody scFv Fragment (9.8B) | WB, ELISA, FuncS | scFv |
| PSBL-043 | Recombinant Mouse Anti-CHIKV VLP Antibody scFv Fragment (CHK152) | WB, ELISA, FuncS | scFv |
| PSBL-044 | Recombinant Mouse Anti-CHIKV VLP Antibody scFv Fragment (m10) | WB, ELISA, FuncS | scFv |
| PSBL-045 | Recombinant Mouse Anti-CHIKV VLP Antibody scFv Fragment (m242) | WB, ELISA, FuncS | scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-042 | Recombinant Mouse Anti-CHIKV VLP Antibody Fab Fragment (9.8B) | WB, ELISA, FuncS | Fab |
| PFBL-043 | Recombinant Mouse Anti-CHIKV VLP Antibody Fab Fragment (CHK152) | WB, ELISA, FuncS | Fab |
| PFBL-044 | Recombinant Mouse Anti-CHIKV VLP Antibody Fab Fragment (m10) | WB, ELISA, FuncS | Fab |
| PFBL-045 | Recombinant Mouse Anti-CHIKV VLP Antibody Fab Fragment (m242) | WB, ELISA, FuncS | Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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