Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Binds actin and the Arp2/3 complex. Interacts with BAIAP2. Component of the WAVE2 complex composed of ABI1, CYFIP1/SRA1, NCKAP1/NAP1 (NCKAP1l/HEM1 in hematopoietic cells) and WASF2/WAVE2 (PubMed:16417406). Directly interacts with BRK1. Interacts with FNBP1L (via the SH3 domain) (PubMed:19798448). (Microbial infection) Interacts with human cytomegalovirus protein UL135.
Actin-binding
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For Research Use Only. Not For Clinical Use.