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WNK3
Anti-WNK3 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
This gene encodes a protein belonging to the with no lysine family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Group enriched (Granulosa cells, Cardiomyocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AF22, AN3-CA, HAP1, NTERA-2, SiHa, SuSa, U-2 OS)
Interaction
Interacts with WNK1 and WNK4.
Molecular function
Kinase, Serine/threonine-protein kinase, Transferase
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