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XAGE1B
Anti-XAGE1B Recombinant Antibody Products
- Recombinant Anti-Human XAGE1B Antibody (MOB-2212z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, FC, FuncS
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- Recombinant Anti-Human XAGE1B Antibody scFv Fragment (MOB-2212z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, Neut, FuncS
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- Recombinant Anti-Human XAGE1B Antibody Fab Fragment (MOB-2212z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, Nert, FuncS
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For Research Use Only. Not For Clinical Use.
This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Spermatogonia, Spermatocytes)
Immune cell specificity
Immune cell enriched (plasmacytoid DC)
Cell line specificity
Cell line enhanced (HMC-1, NB-4, THP-1, U-2 OS, U-266/84, U-937)
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