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For Research Use Only. Not For Clinical Use.


The fibronectins (FNs) comprise a group of extracellular matrix proteins that mediate cell adhesion, migration, proliferation, and differentiation. Diversity in the FNs occurs by alternative splicing in two type III repeats termed EIIIA (or ED-A) and EIIIB (or ED-B) and one non-homologous repeat called V (or IIICS). The EIIIA and EIIIB segments are either entirely included or excluded, whereas the V region may be included, excluded, or partially included in FN.
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