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RPS6KA3

Anti-RPS6KA3 Products

Mouse Anti-RPS6KA3 Recombinant Antibody (clone 5H5-C11-F10) (VS3-QX984)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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Mouse Anti-RPS6KA3 Recombinant Antibody (clone 356CT10.6.1.2) (VS3-XY1386)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB
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Recombinant Rabbit Anti-RPS6KA3 (phospho Ser227) Antibody (clone R01-5B5) (VS3-FY1282)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IP
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Recombinant Rabbit Anti-RPS6KA3 Antibody (clone R05-6E3) (VS3-FY1283)
- Species Reactivity: Human, Hamster
- Type: Rabbit IgG
- Application: WB, IHC-P, IP
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Rabbit Anti-RPS6KA3 (pS227) Recombinant Antibody (VS3-WK2265) (VS3-WK2265)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IP
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Mouse Anti-RPS6KA3 Recombinant Antibody (clone 18G7) (MOB-3927z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, FC, IF
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Hi-Affi™ Recombinant Rabbit Anti-RPS6KA3 Monoclonal Antibody (DS3123AB) (MOR-3123)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP
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Mouse Anti-RPS6KA3 Monoclonal Antibody (VS7-0425-WR795) (VS7-0425-WR795)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IF, ICC, FC, ELISA
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Mouse Anti-RPS6KA3 Monoclonal Antibody (clone 4E10) (VS7-0425-WR799)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ICC, FC
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Anti-RPS6KA3 Immunohistochemistry Kit (VS-0525-XY6224)
- Species Reactivity: Human
- Target: RPS6KA3
- Application: IHC
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For Research Use Only. Not For Clinical Use.

Background

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).

Protein class

Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (Hep G2)

Interaction

Forms a complex with either MAPK1/ERK2 or MAPK3/ERK1 in quiescent cells. Transiently dissociates following mitogenic stimulation (By similarity). Interacts with NFATC4, ETV1/ER81 and FGFR1.

Molecular function

Kinase, Serine/threonine-protein kinase, Transferase

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