This antibody-cytokine fusion protein was achieved by conjugating/fusing the Anti-EpCAM IgG (LSLS-ATAT) to IL2. It was expressed in CHO and purified with affinity chromatography. The immunocytokine retains the ability to bind the EpCAM as well as the biological activity of IL2. Modification of amino acid residues at the junction of immunocytokine fusion proteins to reduce immunogenicity by identifying candidate T-cell epitopes. This immunocytokine was designed for treating solid tumor.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-701 | Anti-Human EpCAM/17-1A Recombinant Antibody (Edrecolomab) | ELISA, IP, FC, FuncS, IF, Neut | IgG2a - kappa |
TAB-363MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-363MZ) | ELISA, FuncS | Mouse IgG1, κ |
TAB-364MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-364MZ) | FC | Mouse IgG1 |
TAB-365MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-365MZ) | FC | Mouse IgG1 |
TAB-366MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-366MZ) | ELISA, FC | Mouse IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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