Afuco™ Anti-Human GNRHR ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-312CL)
Anti-GNRHR ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. Monoclonal antibodies against gonadotropin releasing hormone (GnRH) receptor induce cellular apoptosis of various cancer cells expressing this surface receptor. The monoclonal antibodies can serve as anti-cancer agents for the treatment of cancer in humans, and can function as analogs of GnRH to affect regulation of reproductive functions or fertility in humans.
Specific Inquiry
Normal Tissue
Figure 1 Low expression in rectum
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13424/155895_A_5_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13424/155895_A_5_3_val_selected.jpg
Figure 2 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13424/155895_A_7_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13424/155895_A_7_4.jpg
Figure 3 Testis
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13424/155895_A_6_6.jpg
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13424/155895_A_6_6.jpg
Figure 4 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13424/155895_A_7_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13424/155895_A_7_8.jpg
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions
- Storage
- Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.
Target
- Alternative Names
- GNRHR; gonadotropin-releasing hormone receptor; HH7; GRHR; LRHR; LHRHR; GNRHR1; gnRH-R; gnRH receptor; luliberin receptor; type I GnRH receptor; leutinizing-releasing hormone receptor; leutinizing hormone releasing horomone receptor; gonadotropin-releasing hormone (type 1) receptor 1
- Gene ID
- 2798
- UniProt ID
- P30968
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2575z | Mouse Anti-GNRHR Recombinant Antibody (clone 40A2) | FC, IF, IHC | Mouse IgG1, κ |
| MOB-1747MZ | Recombinant Mouse Anti-Human GNRHR Antibody (clone BU3.H8) | IHC-P, WB | Mouse antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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