Recombinant Anti-HCV C Intrabody [(D-Arg)9] (CAT#: IAB-B075(A))
Recombinant anti-HCV C intrabody linked to (D-Arg)9 works within cells to bind HCV C, expressed in E. coli cells. Intracellular immunization represents a promising antiviral approach to interfere with the life cycle of HCV.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Immunogen
- hepatitis C virus core protein
- Host Species
- human
- Type
- scFv-(D-Arg)9
- Cell Penetrating Peptide
- (D-Arg)9
It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
- Species Reactivity
- HCV
- Applications
- Antibody assay: Western blot; Neutralization; Functional studies
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- HCV; HCV C; Hepatitis C virus; Hepatitis C virus core protein; Hepatitis C virus polyprotein; Genome polyprotein
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Intrabody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B075(G) | Recombinant Anti-HCV C Intrabody [+36 GFP] | ELISA, ICC, FuncS | scFv-(+36GFP) |
| IAB-B075(T) | Recombinant Anti-HCV C Intrabody [Tat] | PCA, Neut, FuncS | scFv-Tat |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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