Recombinant Anti-HIV rev Intrabody [(D-Arg)9] (CAT#: IAB-B015(A))
Recombinant anti-HIV rev intrabody linked to (D-Arg)9 works within cells to bind HIV rev, expressed in E. coli cells.
Specific Inquiry
Specifications
- Immunogen
- human immunodeficiency virus rev protein
- Host Species
- human
- Type
- scFv-(D-Arg)9
- Cell Penetrating Peptide
- (D-Arg)9
It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
- Species Reactivity
- HIV
- Applications
- Formats of immunological tests: Western blot; Immunocytochemistry; Neutralization; Functional studies
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C
Target
- Alternative Names
- HIV rev; Human immunodeficiency virus 1 Rev; Regulator of expression of viral proteins; Protein Rev
- Gene ID
- 155908
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B015(G) | Recombinant Anti-HIV rev Intrabody [+36 GFP] | IF, FC, FuncS | scFv-(+36GFP) |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABS-0142 | Rabbit Anti-HIV Rev Recombinant Antibody (Clone 01JF42) | ELISA, FuncS | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBS-0142 | Rabbit Anti-HIV Rev Recombinant Antibody (Clone 01JF42); Fab Fragment | ELISA, FuncS | Rabbit Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBS-0142 | Rabbit Anti-HIV Rev Recombinant Antibody (Clone 01JF42); scFv Fragment | ELISA, FuncS | Rabbit scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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