Anti-Human CD274 Recombinant Antibody (TAB-417CQ) (CAT#: TAB-417CQ)

Recombinant monoclonal antibody to CD274. This antibody is a human IgG1 monoclonal antibody that targets and binds to PD-L1, a protein that is often overexpressed on the surface of cancer cells and immune cells in the tumor microenvironment.

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ELISA

Figure 1 Anti-Human CD274 Antibody (TAB-417CQ) in ELISA

Figure 1 Anti-Human CD274 Antibody (TAB-417CQ) in ELISA

ELISA analysis of TAB-417CQ was performed by coating with PD-L1 Protein, Human, Recombinant (His Tag).
The secondary antibody: HRP-Anti-Human IgG (H+L)

WB

Figure 2 Anti-Human CD274 Antibody (TAB-417CQ) in WB

Figure 2 Anti-Human CD274 Antibody (TAB-417CQ) in WB

Western blot analysis of TAB-417CQ was performed with PD-L1 Protein, Human, Recombinant (His Tag).
TAB-417CQ incubation concentration: 2ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Lane 1: Reducing antigen (0.1μg)
Lane 2: Reducing antigen (0.3μg)
Lane 3: Reducing antigen (0.6μg)

DB

Figure 3 Anti-Human CD274 Antibody (TAB-417CQ) in DB

Figure 3 Anti-Human CD274 Antibody (TAB-417CQ) in DB

Dot blot analysis of TAB-417CQ was performed with PD-L1 Protein, Human, Recombinant (His Tag).
TAB-417CQ incubation concentration: 2ng/μL.
NC: Negative control PC: Positive control


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG1, κ
  • Specificity
  • Human CD274
  • Species Reactivity
  • Human
  • Applications
  • ELISA, IHC, FC, IP, IF, Inhib, FuncS
  • Conjugate
  • Unconjugated
  • Related Disease
  • Cancers, non-small cell lung (NSCLC), Solid tumors, bladder, urothelial

Product Property

  • Purity
  • > 95% as determined by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Applications

  • Application Notes
  • The CD274 antibody has been reported in applications of ELISA, IHC, FC, IP, IF, Inhib, FuncS.

Target

  • Alternative Names
  • Programmed cell death 1 ligand 1; B7H1; B7-H1; PDL1; PD-L1; PDCD1L1; B7 homolog 1; B7 homologue 1

Related Resources

  • Biosimilar Overview
  • Citations
Please refer to Durvalumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Durvalumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Customer Reviews and Q&As

Customer Review Q&As

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  • Ideal for Durvalumab Studies
    The Durvalumab has been excellent for our PD-L1 studies. Its specificity and sensitivity are top-notch, providing clear and reliable results. This antibody has significantly improved the accuracy of our experiments and saved us a lot of troubleshooting time.
  • Effective in Immunoassays
    We incorporated this antibody into our immunoassays, and it has been a great asset. The specificity for PD-L1 is precise, allowing for accurate detection and analysis. The reliable performance has made it an invaluable tool in our lab.
  • Consistent and High-Quality
    This antibody has proven to be consistent and high-quality in our assays. The reproducible results and strong affinity for PD-L1 have significantly improved our experiments, making it a crucial part of our research toolkit. The consistent performance has greatly enhanced our data quality.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TAB-417CQ, RRID: AB_3111930)

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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