Mouse Anti-lipid A Recombinant Antibody (clone S1-15) (CAT#: PABL-262)
Recombinant Mouse Antibody (S1-15) is capable of binding to Lipid A.
Specific Inquiry
Figure 1 Quantitative conjugate ELISAs coated with graded concentrations of neoglycoconjugates corresponding to 2.5 (blue triangle), 5 (green triangle), 10 (red circle), and 20 (black square) pmol of ligand per well and reacted with mAbs (A) S1–15 and (B) A6 at concentrations indicated on the x axis are shown.
Ligands used were bisphosphorylated lipid A backbone conjugated to BSA (BBP-divinyl sulfone BSA, left panel) and 4′-monophosphorylated lipid A backbone conjugated to BSA (right panel), and absorbance was measured at 405 nm. The chemical structure of the carbohydrate backbone of lipid A (BBP) used for crystallization trials (C). 1P and 4P refer to the position of the phosphates on the pyranose ring.
Haji-Ghassemi, O., Müller-Loennies, S., Rodriguez, T., Brade, L., Kosma, P., Brade, H., & Evans, S. V. (2015). Structural Basis for Antibody Recognition of Lipid A INSIGHTS TO POLYSPECIFICITY TOWARD SINGLE-STRANDED DNA.Journal of Biological Chemistry, 290(32), 19629-19640.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG
- Clone
- S1-15
- Applications
- ELISA, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- lipid A; the endotoxic principle of LPS; LPS
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-261 | Mouse Anti-lipid A Recombinant Antibody (clone A6) | ELISA, FuncS | Mouse IgG |
| PABL-263 | Mouse Anti-lipid A Recombinant Antibody (clone S55-3) | ELISA, FuncS | Mouse IgG |
| MOB-159CQ | Goat Anti-Lipid A Polyclonal Antibody | ELISA, WB, IF, IHC | Goat IgG |
| PABS-0119 | Mouse Anti-Lipid A Recombinant Antibody (Clone S55-5) | ELISA, FuncS | Mouse IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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