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Anti-Human CD274 Recombinant Antibody (Atezolizumab) (CAT#: TAB-418CQ)

Recombinant monoclonal antibody to CD274. Atezolizumab is a human monoclonal antibody that can be potentially used in the treatment of Cancers, non-small cell lung (NSCLC), Solid tumors, bladder, urothelial.

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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-251 MG
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3528/1899_B9_6_cr5ba2049576272_selected.jpg
Figure 2 IF staining of human cell line BJ
Figure 2 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3528/1936_G3_3_blue_red_green.jpg
Figure 3 IF staining of human cell line U-2 OS
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3528/1953_G5_3_blue_red_green.jpg
Normal Tissue
Figure 4 Colon
Figure 4 Colon
(Peripheral nerve/ganglion
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76385/169546_A_9_3.jpg
Figure 5 Placenta
Figure 5 Placenta
(Cytotrophoblasts
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Syncytiotrophoblasts - cell body
Staining:Medium
Intensity: Moderate
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining:High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76385/169546_A_1_7.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, HHSteC, U-251 MG)
Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, HHSteC, U-251 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120217-CD274

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • IgG1, κ
  • Specificity
  • Human CD274
  • Species Reactivity
  • Human
  • Applications
  • Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry
  • Conjugate
  • Unconjugated
  • CAS
  • 1380723-44-3
  • Generic Name
  • Atezolizumab
  • UNII
  • 52CMI0WC3Y
  • Related Disease
  • Cancers, non-small cell lung (NSCLC), Solid tumors, bladder, urothelial

Product Property

  • Purity
  • > 95% as determined by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • Programmed cell death 1 ligand 1; B7H1; B7-H1; PDL1; PD-L1; PDCD1L1; B7 homolog 1; B7 homologue 1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Atezolizumab"

Afuco™ Anti-CD274 ADCC Recombinant Antibody (Atezolizumab), ADCC Enhanced
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD274. Atezolizumab is a human monoclonal antibody that can be potentially used in the treatment of Cancers, non-small cell lung (NSCLC), Solid tumors, bladder, urothelial.

See other products for "Cd274"

Select a product category from the dropdown menu below to view related products.
Please select product type
Single Domain Antibody Products Fab Antibody Products Humanized Antibody Products Chimeric Antibody Products Mouse Antibody Products Human Antibody Products Neutralizing Antibody Products Blocking Antibody Products Rabbit Monoclonal Antibody Products IgG Antibody Products ADCC Enhanced Antibody Products ScFv Antibody Products Hexamer Antibody Products Non-Human Primate (NHP) Antibody Products
CAT Product Name Application Type
NAB-305-sdAb Recombinant Anti-Mouse Cd274 VHH Single Domain Antibody IHC, IP, FC, Neut, FUNC Llama VHH
HPAB-N0408-YC-VHH Recombinant Humanized Anti-CD274 Single Domain Antibody (HPAB-N0408-YC-VHH) ELISA, FC, BL Human VHH
HPAB-N0307-YC-VHH Recombinant Humanized Anti-CD274 Single Domain Antibody (HPAB-N0307-YC-VHH) ELISA, FC, BL Humanized VHH
NBD-0065-YJ-VHH Camelid Anti-CD274 Recombinant Single Domain Antibody (NBD-0065-YJ-VHH) ELISA Camelid VHH
NBD-0066-YJ-VHH Camelid Anti-CD274 Recombinant Single Domain Antibody (NBD-0066-YJ-VHH) ELISA, Inihb Camelid VHH

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To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TAB-418CQ, RRID: AB_3111931)

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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