BV421-A*24:02/Human LY6K (RYCNLEGPPI) MHC Tetramer (CAT#: MHC-LC083)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of LY6K-derived peptide of RYCNLEGPPI sequence covering 177-186 and A*24:02 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SiHa
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17770/1611_E1_4_selected.jpg
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17770/1611_E1_4_selected.jpg
Figure 2 IHC staining of human testis
(High expression. RNA expression: nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17770/159279_A_6_6_selected.jpg
(High expression. RNA expression: nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17770/159279_A_6_6_selected.jpg
Figure 3 IHC staining of human endometrium
(Low expression. RNA expression: nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17770/159279_B_5_3_val_selected.jpg
(Low expression. RNA expression: nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17770/159279_B_5_3_val_selected.jpg
Figure 4 IHC staining of human small intestine
(Low expression. RNA expression: nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79929/170639_A_4_2_val_selected.jpg
(Low expression. RNA expression: nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79929/170639_A_4_2_val_selected.jpg
Figure 5 Kidney
(Cells in tubules
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17770/159279_A_8_5.jpg
(Cells in tubules
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17770/159279_A_8_5.jpg
Figure 6 Testis
(Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75742/159151_A_6_6.jpg
(Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75742/159151_A_6_6.jpg
Figure 7 RNA cell line category: Cell line enhanced (A-431, BJ, HeLa, SiHa, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160886-LY6K
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160886-LY6K
Specifications
- Allele
- A*24:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- LY6K
- Antigen Species
- Human
- Peptide
- RYCNLEGPPI
- Range
- 177-186
- Conjugate
- BV421
- Application
- FCM
Target
- Antigen Introduction
- Lymphocyte antigen 6K is a protein that in humans is encoded by the LY6K gene.
- Alternative Names
- LY6K; Lymphocyte antigen 6 family member K; CT97; ly-6K; URLC10; HSJ001348
- Gene ID
- 54742
- UniProt ID
- Q17RY6
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MHC Tetramer Products for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC081 | PE-A*24:02/Human LY6K (RYCNLEGPPI) MHC Tetramer | FCM | |
| MHC-LC082 | APC-A*24:02/Human LY6K (RYCNLEGPPI) MHC Tetramer | FCM | |
| MHC-CN0989 | PE-A*02:01/Human LY6K (LLLASIAAGL) MHC Tetramer | FCM, IHC | |
| MHC-CN0990 | APC-A*02:01/Human LY6K (LLLASIAAGL) MHC Tetramer | FCM, IHC | |
| MHC-CN0991 | FITC-A*02:01/Human LY6K (LLLASIAAGL) MHC Tetramer | FCM, IHC |
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