PE-A*02:01/Human PPP2R1B (SLLPAIVEL) MHC Tetramer (CAT#: MHC-LC2358)

• Allele
• A*02:01

• Class
• Class I

• MHC Species
• Human

• Antigen
• PPP2R1B

• Antigen Species
• Human

• Peptide
• SLLPAIVEL

• Range
• 415-423

• Conjugate
• PE

• Application
• FCM

• Antigen Introduction
• This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]

• Alternative Names
• PPP2R1B; Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; PR65B; PP2A-Abeta

• Gene ID
• 5519

• UniProt ID
• P30154

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