PE-DRB5*01:01/Human PDYN (YGGFLRRIRPKLK) MHC Tetramer (CAT#: MHC-LC2127)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PDYN of peptide YGGFLRRIRPKLK covering 207-219 and DRB5*01:01 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Low expression in vagina
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53342/168158_B_2_2_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53342/168158_B_2_2_val_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (THP-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101327-PDYN
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101327-PDYN
Specifications
- Allele
- DRB5*01:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- PDYN
- Antigen Species
- Human
- Peptide
- YGGFLRRIRPKLK
- Range
- 207-219
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
- Alternative Names
- PDYN; Beta-neoendorphin-dynorphin precursor; ADCA; PENKB; SCA23
- Gene ID
- 5173
- UniProt ID
- P01213
Related Resources
Cocaine Addiction
Amphetamine Addiction
Alcoholism
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2205z | Mouse Anti-PDYN Recombinant Antibody (clone 20A6) | WB, ELISA, IP | Mouse IgG2a, κ |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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