PE-DRB5*01:01/Human PDYN (LRRIRPKLK) MHC Tetramer (CAT#: MHC-LC2126)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PDYN of peptide LRRIRPKLK covering 211-219 and DRB5*01:01 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Low expression in vagina
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53342/168158_B_2_2_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53342/168158_B_2_2_val_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (THP-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101327-PDYN
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101327-PDYN
Specifications
- Allele
- DRB5*01:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- PDYN
- Antigen Species
- Human
- Peptide
- LRRIRPKLK
- Range
- 211-219
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
- Alternative Names
- PDYN; Beta-neoendorphin-dynorphin precursor; ADCA; PENKB; SCA23
- Gene ID
- 5173
- UniProt ID
- P01213
Related Resources
Cocaine Addiction
Amphetamine Addiction
Alcoholism
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2205z | Mouse Anti-PDYN Recombinant Antibody (clone 20A6) | WB, ELISA, IP | Mouse IgG2a, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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