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    PE-Mamu-A1*002:01/Human CNN3 (ASQKGMSVY) MHC Tetramer (CAT#: MHC-LC4499)

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human CNN3 of peptide ASQKGMSVY covering 253-261 and Mamu-A1*002:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

    Specific Inquiry
    • Size:
    Custom Production

    MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

    Peptide Sequence *:
    Allele Requested *:
    Antigen Species:
    Antigen Molecule:
    Sequence Position:
    Form Requested *:
    Conjugation *:
    Size *:
    Comments:

    Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & actin filaments.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/51237/if_selected.jpg
    Normal Tissue
    Figure 2 Placenta
    Figure 2 Placenta
    (High expression in placenta)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/51237/125050_A_1_7_val_selected.jpg
    Figure 3 Kidney
    Figure 3 Kidney
    (Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/9849/27252_A_7_5.jpg
    Figure 4 Testis
    Figure 4 Testis
    (Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/9849/27252_A_4_6.jpg
    Figure 5 Smooth muscle
    Figure 5 Smooth muscle
    (Smooth muscle cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/9849/27252_B_4_7.jpg
    Figure 6 Cerebral cortex
    Figure 6 Cerebral cortex
    (Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/9849/27252_B_7_5.jpg
    Figure 7 Colon
    Figure 7 Colon
    (Endothelial cells Staining: High Intensity: Strong Quantity:>75% Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Microvilli Staining: High Intensity: Strong Fibroblasts Staining: Low Intensity: Weak Goblet cells Staining: High Intensity: Strong Quantity:>75% Peripheral nerve/ganglion Staining: High Intensity: Strong)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/9849/27252_A_9_3.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000117519-CNN3

    Specifications

    • Allele
    • Mamu-A1*002:01
    • Class
    • Class I
    • MHC Species
    • Macaca
    • Antigen
    • CNN3
    • Antigen Species
    • Human
    • Peptide
    • ASQKGMSVY
    • Range
    • 253-261
    • Conjugate
    • PE
    • Application
    • FCM

    Target

    • Antigen Introduction
    • This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction. [provided by RefSeq, Jul 2008]
    • Alternative Names
    • CNN3; Calponin-3

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "CNN3"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
    CAT Product Name Application Type
    VS3-FY2671 Mouse Anti-CNN3 Recombinant Antibody (VS3-FY2671) WB, IHC, ICC, FC, ELISA Mouse IgG
    VS7-HM754 Mouse Anti-CNN3 Recombinant Antibody (clone 5E4E4) WB, IHC, ICC, FCM Mouse IgG1
    VS7-HM755 Mouse Anti-CNN3 Recombinant Antibody (clone 6D4B10) FCM Mouse IgG1

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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