Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) (CAT#: Gly-163LC)
This product is a sialylated chimeric (mouse/human) monoclonal antibody. The antibody Infliximab with enhanced anti-inflammatory properties specficfically binds to human TNFα and can be potentially used in the treatment of Autoimmune diseases.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Tonsil
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78469/168112_A_4_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78469/168112_A_4_8.jpg
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000232810-TNF
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000232810-TNF
Glyco-engineering
- Glycosylation site
- Asn297 in Fc region
- Glycoform (ratio)
- G1FS1, G2FS1, G2FS2
- Glycosylation Type
- N-glycosylation
- Activity
- Enhanced anti-inflammatory
Specifications
- Target
- TNFα (Tumor necrosis factor alpha)
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric antibody (mouse/human)
- Specificity
- Human
- Clone
- Infliximab
- Expression Host
- CHO
- Applications
- ELISA
Target
- Alternative Names
- TNF; DIF; TNFA; TNFSF2; TNF-alpha; tumor necrosis factor
- Related Disease
- Autoimmune diseases
- Gene ID
- 7124
- UniProt ID
- P01375
Related Resources
Asthma
Inflammatory Bowel Diseases
TNF Signaling Pathway
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone Infliximab"
See other products for "TNF"
Select a product category from the dropdown menu below to view related products.
Please select product type
Chimeric Antibodies
Rat Antibodies
Humanized Antibodies
IgM Antibodies
Mouse Antibodies
Human Antibodies
Fc Glycosylation Antibodies
Non-hyper Galactosylated Antibodies
Sialylated IgG Glycan
Hyper-galactosylated Antibodies
Chicken IgY Antibodies
Blocking Antibodies
Neutralizing Antibodies
Rabbit Monoclonal Antibodies
ScFv Antibodies
Fab Antibodies
IgG Antibodies
ADCC Enhanced Antibodies
Single Domain Antibodies
Antibody Magnetic Beads
ScFv-Fc Chimeras
FC Reagents & Kits
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-006 | Anti-Human TNF Recombinant Antibody (Infliximab) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
| TAB-148CQ | Anti-Human TNF Recombinant Antibody | ELISA | Chimeric antibody (mouse/human) |
| TAB-402CQ | Human Anti-TNF Recombinant Antibody (TAB-402CQ) | ELISA | Chimeric (mouse/human) IgG |
| TAB-148CQ-S(P) | Anti-Human TNF Recombinant Antibody scFv Fragment | ELISA | Chimeric antibody (mouse/human) |
| TAB-148CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment | ELISA | Chimeric antibody (mouse/human) |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for Gly-163LC. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
-5.jpg)
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA
-3.jpg)
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
