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Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) (CAT#: Gly-163LC)

This product is a sialylated chimeric (mouse/human) monoclonal antibody. The antibody Infliximab with enhanced anti-inflammatory properties specficfically binds to human TNFα and can be potentially used in the treatment of Autoimmune diseases.

See more Glyco-Engineering Antibody products for TNF
Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
Figure 1 Tonsil
Figure 1 Tonsil
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78469/168112_A_4_8.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000232810-TNF
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000232810-TNF

Glyco-engineering

  • Glycosylation site
  • Asn297 in Fc region
  • Glycoform (ratio)
  • G1FS1, G2FS1, G2FS2
  • Glycosylation Type
  • N-glycosylation
  • Activity
  • Enhanced anti-inflammatory

Specifications

  • Target
  • TNFα (Tumor necrosis factor alpha)
  • Host Species
  • Human
  • Derivation
  • Chimeric (mouse/human)
  • Type
  • Chimeric antibody (mouse/human)
  • Specificity
  • Human
  • Clone
  • Infliximab
  • Expression Host
  • CHO
  • Applications
  • ELISA

Target

  • Alternative Names
  • TNF; DIF; TNFA; TNFSF2; TNF-alpha; tumor necrosis factor
  • Related Disease
  • Autoimmune diseases

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone Infliximab"

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Human Antibody Chimeric Antibody Rat Antibody Recombinant Antibody Mouse Antibody Humanized Antibody Single-domain Antibody Fc Glycosylation Non-hyper Galactosylated Sialylated IgG Glycan Hyper-galactosylated Chicken IgY Antibody Blocking Antibody Neutralizing Antibody Rabbit Monoclonal Antibody scFv Fragment Antibody Fab Fragment Antibody ADCC Enhanced Antibody
CAT Product Name Application Type
TAB-010 Anti-Human TNF Recombinant Antibody (TAB-010) WB, FC, IP, ELISA, Neut, FuncS, IF IgG1, κ
TAB-111CQ-F(E) Anti-Human TNF Recombinant Antibody Fab Fragment (B5) ELISA, WB Human antibody
TAB-113CQ-F(E) Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-113CQ-F(E)) ELISA Human Fab
TAB-404CQ-F(E) Anti-Human TNF Recombinant Antibody Fab Fragment (BPC1494) ELISA, WB Human antibody
TAB-405CQ-F(E) Anti-Human TNF Recombinant Antibody Fab Fragment (XENP6401) ELISA Human antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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