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Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) (CAT#: Gly-163LC)

This product is a sialylated chimeric (mouse/human) monoclonal antibody. The antibody Infliximab with enhanced anti-inflammatory properties specficfically binds to human TNFα and can be potentially used in the treatment of Autoimmune diseases.

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  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
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Normal Tissue
Figure 1 Tonsil
Figure 1 Tonsil
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78469/168112_A_4_8.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000232810-TNF
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000232810-TNF

Glyco-engineering

  • Glycosylation site
  • Asn297 in Fc region
  • Glycoform (ratio)
  • G1FS1, G2FS1, G2FS2
  • Glycosylation Type
  • N-glycosylation
  • Activity
  • Enhanced anti-inflammatory

Specifications

  • Target
  • TNFα (Tumor necrosis factor alpha)
  • Host Species
  • Human
  • Derivation
  • Chimeric (mouse/human)
  • Type
  • Chimeric antibody (mouse/human)
  • Specificity
  • Human
  • Clone
  • Infliximab
  • Expression Host
  • CHO
  • Applications
  • ELISA

Target

  • Alternative Names
  • TNF; DIF; TNFA; TNFSF2; TNF-alpha; tumor necrosis factor
  • Related Disease
  • Autoimmune diseases

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Downloads

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Chimeric Antibody Products Mouse Antibody Products Rat Antibody Products Fab Antibody Products Humanized Antibody Products IgM Antibody Products Human Antibody Products Fc Glycosylation Antibody Products Non-hyper Galactosylated Antibody Products Sialylated IgG Glycan Products Hyper-galactosylated Antibody Products Chicken IgY Antibody Products Neutralizing Antibody Products Blocking Antibody Products Rabbit Monoclonal Antibody Products IgG Antibody Products ADCC Enhanced Antibody Products Single Domain Antibody Products ScFv Antibody Products Antibody Magnetic Beads
CAT Product Name Application Type
TAB-006 Anti-Human TNF Recombinant Antibody (Infliximab) IF, IP, Neut, FuncS, ELISA, FC, WB IgG1 - kappa
TAB-148CQ-S(P) Anti-Human TNF Recombinant Antibody scFv Fragment ELISA Chimeric antibody (mouse/human)
TAB-402CQ-S(P) Mouse Anti-TNF Recombinant Antibody; scFv Fragment (TAB-402CQ-S(P)) ELISA Mouse scFv
TAB-148CQ-F(E) Anti-Human TNF Recombinant Antibody Fab Fragment ELISA Chimeric antibody (mouse/human)
TAB-402CQ-F(E) Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-402CQ-F(E)) ELISA Chimeric (mouse/human) Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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