Recombinant Mouse Anti-A. castellanii Antibody (AMEC1) (CAT#: FAMAB-0007YC)

Acanthamoeba species are ubiquitous soil and freshwater protozoa that have been associated with infections of the human brain, skin, lungs and eyes. The specific antibody, clone AMEC1, binds to cysts but not trophozoites of the environmental group I species, Acanthamoeba tubiashi.


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FC

Figure 1 Mouse Anti-A. castellanii Antibody (AMEC1) in FC.

Figure 1 Mouse Anti-A. castellanii Antibody (AMEC1) in FC.

Flow cytometry histograms demonstrating reactivity of eight monoclonal antibodies with cysts and trophozoites of unfixed Acanthamoeba castellanii AC112.

Turner, M. L. , Cockerell, E. J. , Brereton, H. M. , Badenoch, P. R. , Tea, M. , & Coster, D. J. , et al. (2005). Antigens of selected acanthamoeba species detected with monoclonal antibodies. International Journal for Parasitology, 35(9), 981-990.

IHC

Figure 2 Mouse Anti-A. castellanii Antibody (AMEC1) in IHC.

Figure 2 Mouse Anti-A. castellanii Antibody (AMEC1) in IHC.

Indirect immunoperoxidase staining with MTAC3, MTAC4 and AMEC1 on sections of an Acanthamoeba-infected human cornea. No counterstain was applied to the preparations. The anterior surface of the cornea is on the left. (A) MTAC3; (B) MTAC4; (C) MTAC4; (D) AMEC1; (E) MTAC3; (F) Giemsa-stained section of the same cornea shown for comparative purposes. Original magnification: ×120 (panels A, B, F), ×320 (panels C, D, E). Scale bar = 10 μm.

Turner, M. L. , Cockerell, E. J. , Brereton, H. M. , Badenoch, P. R. , Tea, M. , & Coster, D. J. , et al. (2005). Antigens of selected acanthamoeba species detected with monoclonal antibodies. International Journal for Parasitology, 35(9), 981-990.


Specifications

  • Immunogen
  • Live trophozoites, cysts
  • Host Species
  • Mouse
  • Type
  • Mouse IgM, κ
  • Specificity
  • A. castellanii
  • Species Reactivity
  • A. castellanii
  • Clone
  • AMEC1
  • Applications
  • Flow Cytometry, Immunohistochemistry
  • Related Disease
  • Acanthamoeba infection

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • Acanthamoeba castellanii; A. castellanii

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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