Rabbit Anti-DYSF Recombinant Antibody (VS13-YC332) (CAT#: VS13-YC332)
The Rabbit Anti-DYSF Recombinant Antibody is specific for human and mouse DYSF. DYSF encodes dysferlin, a membrane fusion-related protein impacting muscle repair mechanisms, with mutations linked to muscular dystrophies like LGMD2B. The anti-DYSF antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry (1/50-1/100), Immunofluorescence (1/50-1/200).
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Immunofluorescent staining of human cell line RH-30 shows localization to plasma membrane & centriolar satellites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17071/1150_E3_3_selected.jpg

(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21945/49019_A_8_3.jpg

(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21945/49019_A_8_5.jpg

(Leydig cells Staining: Low Intensity: Weak Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21945/49019_A_5_6.jpg

(Myocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21945/49019_B_2_6.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135636-DYSF
Specifications
- Immunogen
- Recombinant human Dysferlin.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse DYSF
- Species Reactivity
- Human, Mouse
- Applications
- WB, IHC-P, ICC, IF
- Conjugate
- NONE
- Related Disease
- Miyoshi Muscular Dystrophy
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4) containing 150 mM NaCl and 50% Glycerol.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Immunofluorescence (IF): 1/50-1/200
Target
- Alternative Names
- Dysferlin; Limb Girdle Muscular Dystrophy 2B (Autosomal Recessive); Fer-1-Like Family Member 1; Fer-1-Like Protein 1; FER1L1; Dystrophy-Associated Fer-1-Like Protein; Dystrophy-Associated Fer-1-Like 1; LGMD2B; MMD1;
- Gene ID
- 8291
- UniProt ID
- O75923
- Long Name
- Dysferlin
- Cellular Localization
- Cell membrane; Cytoplasmic vesicle membrane
- Protein Refseq
- NP_001123927.1; NP_001124448.1
- Function
- Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion.
Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "DYSF"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-3313z | Mouse Anti-DYSF Recombinant Antibody (clone 26B1) | WB, IP, IF, ELISA | Mouse IgG3 |
MRO-0504-CN | Rabbit Anti-DYSF Recombinant Antibody (clone JF05-54) | WB, IF, IHC | Rabbit IgG |
MRO-1828-CN | Rabbit Anti-DYSF Polyclonal Antibody (MRO-1828-CN) | WB, IHC, FC | Rabbit IgG |
VS3-XY3341 | Rabbit Anti-DYSF Recombinant Antibody (clone R02-4B1) | WB, IHC-P, ICC, IF | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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