Human Anti-EBV Recombinant Antibody (clone AMM01) (CAT#: HPAB-A1237-YJ)
This product is a Human antibody that recognizes EBV.
Specific Inquiry
BLI
Figure 1 AMMO1 binding to gH/gL pre-incubated with the indicated concentrations of gp42 (left) or gp42-T175A (right) was measured by BLI.
Snijder, J., Ortego, M. S., Weidle, C., Stuart, A. B., Gray, M. D., McElrath, M. J., ... & McGuire, A. T. (2018). An antibody targeting the fusion machinery neutralizes dual-tropic infection and defines a site of vulnerability on Epstein-Barr virus. Immunity, 48(4), 799-811.
Neut
Figure 2 Isolated MAb neutralizes EBV infection in epithelial cells and B cells.
EBV fusion machinery (gH/gL and gB)
Snijder, J., Ortego, M. S., Weidle, C., Stuart, A. B., Gray, M. D., McElrath, M. J., ... & McGuire, A. T. (2018). An antibody targeting the fusion machinery neutralizes dual-tropic infection and defines a site of vulnerability on Epstein-Barr virus. Immunity, 48(4), 799-811.
Block
Figure 3 B cell surface staining with SA-PE alone, SA-PE conjugated to biotinylated gH/gL, biotinylated gB, or biotinylated gH/gL bound to gp42 +/− an excess of the indicated MAbs.
Snijder, J., Ortego, M. S., Weidle, C., Stuart, A. B., Gray, M. D., McElrath, M. J., ... & McGuire, A. T. (2018). An antibody targeting the fusion machinery neutralizes dual-tropic infection and defines a site of vulnerability on Epstein-Barr virus. Immunity, 48(4), 799-811.
ELISA
Figure 4 Quantitation of antigen binding to human B cells from different individuals (n = 3-7) engineered to express emAbs.
the HIV-1 broadly neutralizing antibody VRC01 (HIV-emAb), the influenza broadly neutralizing antibody MEDI8852 (Flu-emAb), the EBV neutralizing antibody AMM01 (EBV-emAb), or RSVemAb.
Moffett, H. F., Harms, C. K., Fitzpatrick, K. S., Tooley, M. R., Boonyaratanakornkit, J., & Taylor, J. J. (2019). B cells engineered to express pathogen-specific antibodies protect against infection. Science immunology, 4(35), eaax0644.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- EBV EBV
- Species Reactivity
- EBV
- Clone
- AMM01
- Applications
- Neut
Product Property
- Purification
- Protein A/G Purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- See the COA
- Buffer
- PBS
- Storage
- Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Neutralization.
Target
- Alternative Names
- EB virus; Epstein-Barr virus; EBV; Epstein-Barr virus; Herpesviridae; Human herpesvirus 4; HHV-4
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "EBV"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-299 | Recombinant Anti-EBV Antibody | WB, IHC, FuncS | IgG |
| MHH-299 | Recombinant Human Anti-EBV Antibody | ELISA, IF, FuncS | IgG |
| FAMAB-0109WJ | Human Anti-EBV Recombinant Antibody (clone 123AV16-1) | ELISA, IHC, Inhib | Human IgA1, λ2 |
| FAMAB-0541WJ | Human Anti-EBV Recombinant Antibody (clone F5.2) | ELISA, WB, Neut | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-299-F(E) | Recombinant Anti-EBV Antibody Fab Fragment | RIA, IF, FuncS | Fab |
| MHH-299-F(E) | Recombinant Human Anti-EBV Antibody Fab Fragment | RIA, IF, FuncS | Fab |
| FAMAB-0109WJ-F(E) | Human Anti-EBV Recombinant Antibody (clone 123AV16-1); Fab Fragment | ELISA, IHC | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-299-S(P) | Recombinant Anti-EBV Antibody scFv Fragment | WB, Neut, FuncS | scFv |
| MHH-299-S(P) | Recombinant Human Anti-EBV Antibody scFv Fragment | WB, FC, FuncS | scFv |
| FAMAB-0109WJ-S(P) | Human Anti-EBV Recombinant Antibody (clone 123AV16-1); scFv Fragment | ELISA, IHC | Human scFv |
MHC Tetramer for Virology
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1086 | Hi-Affi™ Rabbit Anti-EBV Recombinant Antibody (clone DS1086AB) | IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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