Mouse Anti-EV71 VP1 Recombinant Antibody (clone D5)

CAT#: VS-0224-XY44

The product is a mouse antibody clone D5 that binds to EV71 particles. D5 is indeed able to neutralize a variety of EV71 genotypes and strains. Moreover, D5 could potently confer protection in a mouse model of EV71 infection. Since the conserved VP1 GH-loop is involved in EV71 binding with its uncoating receptor, the scavenger receptor class B, member 2 (SCARB2), the broadly neutralizing ability of D5 might attribute to its inhibition of EV71 from binding SCARB2.

Specifications

  • Immunogen
  • Recombinant EV71 VLP
  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • EV71 VP1
  • Species Reactivity
  • EV71
  • Clone
  • D5
  • Applications
  • ELISA, Flow Cytometry, Functional assay, Neutralization assay
  • Related Disease
  • Poliomyelitis; Aseptic meningitis

Product Property

  • Purification
  • Protein G purified
  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Format
  • Liquid
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • EV71; VLP; EV71 particle; EV71 F-particle; EV71 E-particle
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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