Recombinant Human Anti-HeV G Antibody (m102.3) (CAT#: PABC-398)
This product is a recombinant Human antibody that can recognize HeV G. m102.3 binds to NiV-G and HeV-G.
Specific Inquiry
Neut
Figure 1 Neutralization efficacy of wild-type and neutralization-escape mutants by m102.4 mAb, m102.4 Fab and m102.3 Fab.
Wild-type (WT) Nipah (NiV) and Hendra (HeV) viruses and their respective m102.4 neutralization escape mutants NiV-V5071 and HeV-D582N were used to evaluate the neutralization efficacy of m102.4 mAb, m102.4 Fab and m102.3 Fab. Starting concentration of m102.4 was 100 mg/mL. The mAb and Fab concentrations at which 50% of the virus was neutralized are plotted.
Xu, K., Rockx, B., Xie, Y., DeBuysscher, B. L., Fusco, D. L., Zhu, Z., ... & Feldmann, H. (2013). Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody. PLoS pathogens, 9(10), e1003684.
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- HeV G
- Species Reactivity
- HeV, NiV
- Clone
- m102.3
- Applications
- Neut, ELISA
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- The antibody m102.3 has been reported in applications of Neutralization and Enzyme-linked Immunosorbent Assay. It's recommended that the optimal antibody concentration, dilution, incubition time etc. be carefully titrated in specific assays. In the neutralization test, mAb m102.3 was used in an amount of 100 μg or 10 μg.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0426CQ | Recombinant Human Anti-HeV G Antibody (m102) | WB | IgG |
| EPAF-0427CQ | Recombinant Human Anti-HeV G Antibody (m101) | WB | IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0198CQ | Human Anti-HeV G Recombinant Antibody (HPAB-0198CQ) | ELISA, WB | Human IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0198CQ-F(E) | Human Anti-HeV G Recombinant Antibody; Fab Fragment (HPAB-0198CQ-F(E)) | ELISA | Human Fab |
| PFBC-398 | Recombinant Human Anti-HeV G Antibody Fab Fragment (m102.3) | ELISA, Neut | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0198CQ-S(P) | Human Anti-HeV G Recombinant Antibody; scFv Fragment (HPAB-0198CQ-S(P)) | ELISA | Human scFv |
| PSBC-398 | Recombinant Human Anti-HeV G Antibody scFv Fragment (m102.3) | ELISA, Neut | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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