Mouse Anti-HIV-1 Gag Recombinant Antibody (clone M12) (CAT#: MRO-2873CQ)

Recombinant mouse antibody to Gag(408-417). The antibody is reactive with p53.


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ELISA

Figure 1 Plasmids expressing GFP or ADAP/GFP or M12/GFP were transfected together with the luciferase reporter plasmid into Jurkat cells to assess the luciferase activity after anti-CD3/CD28 (left panel, P < 0.0001) or anti-CD3/CD80-Fc (right panel, P < 0.05) stimulation.

Figure 1 Plasmids expressing GFP or ADAP/GFP or M12/GFP were transfected together with the luciferase reporter plasmid into Jurkat cells to assess the luciferase activity after anti-CD3/CD28 (left panel, P < 0.0001) or anti-CD3/CD80-Fc (right panel, P < 0.05) stimulation.

Wei, B., Han, L., Abbink, T. E., Groppelli, E., Lim, D., Thaker, Y. R., ... & Jolly, C. (2013). Immune adaptor ADAP in T cells regulates HIV-1 transcription and cell-cell viral spread via different co-receptors. Retrovirology, 10(1), 101.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG1, κ
  • Specificity
  • Recognizes HIV-1 Gag(408-417)
  • Species Reactivity
  • HIV-1
  • Clone
  • M12
  • Applications
  • WB, ELISA

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 Gag antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Gag

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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