Human Anti-HIV-1 gp120 Recombinant Antibody (clone 1E12) (CAT#: PABC-292)
This product is a recombinant Human antibody that can recognize HIV-1 gp120.
Specific Inquiry
Neut
Figure 1 Human Anti-HIV-1 gp120 Antibody (clone 1E12) in Neut.
Neutralization mapping of immunized RM sera, and autologous plasma and mAbs from HIV+ subject Z1800M.
Welbourn, S., Chakraborty, S., Yang, J. E., Gleinich, A. S., Gangadhara, S., Khan, S., ... & Derdeyn, C. A. (2022). A neutralizing antibody target in early HIV-1 infection was recapitulated in rhesus macaques immunized with the transmitted/founder envelope sequence. PLoS pathogens, 18(5), e1010488.
Neut
Figure 2 Human Anti-HIV-1 gp120 Antibody (clone 1E12) in Neut.
Monoclonal antibodies isolated from neutralization positive RM RLk17. 54 RLk17 mAbs recovered using the T/F Env gp120-specific B cell sort were tested in ELISA for binding to the Z1800M T/F Env gp120 protein starting at 5 μg/ml in (A) and for neutralization of the Z1800M T/F Env PV in the TZM-bl assay starting at 25 μg/ml in (B). The bnAb VRC01; the anti-influenza HA mAb EM4C04, and the Z1800M neutralizing mAbs 1A and 1E12 are also shown.
Welbourn, S., Chakraborty, S., Yang, J. E., Gleinich, A. S., Gangadhara, S., Khan, S., ... & Derdeyn, C. A. (2022). A neutralizing antibody target in early HIV-1 infection was recapitulated in rhesus macaques immunized with the transmitted/founder envelope sequence. PLoS pathogens, 18(5), e1010488.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- HIV-1 gp120
- Species Reactivity
- HIV-1
- Clone
- 1E12
- Applications
- Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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See other products for "Clone 1E12"
See other products for "HIV-1 gp120"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-082 | Recombinant Anti-HIV-1 gp120 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
| MRO-028LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91C2) | ELISA | Single domain antibody |
| MRO-029LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91F10) | ELISA | Single domain antibody |
| MRO-030LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91E1) | ELISA | Single domain antibody |
| MRO-031LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91B5) | ELISA | Single domain antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-135 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PGT135) | ELISA, Neut | Human IgG |
| PABL-142 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 412d) | Neut, WB, ELISA, FuncS | Human IgG |
| PABL-155 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC03) | WB, ELISA, Neut, FuncS | Human IgG |
| PABL-156 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC-CH31) | WB, ELISA, Neut, FuncS | Human IgG |
| PABL-160 | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone 59.1) | WB, ELISA, FuncS | Mouse IgG1, κ |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-005LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-005LC) | ELISA | Human IgG1 |
| MRO-006LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-006LC) | ELISA | Human IgG1 |
| MRO-007LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-007LC) | ELISA | Human IgG1 |
| MRO-011LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-011LC) | ELISA | Human IgG1 |
| MRO-012LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-012LC) | ELISA | Human IgG1 |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-135LC | Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) | ELISA, WB, Neut | Chimeric antibody (mouse/human) |
| MRO-135LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
| MRO-135LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-041LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (D59/A2) | ELISA | Mouse antibody |
| MRO-042LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (F58/H3) | ELISA | Mouse antibody |
| MRO-043LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (P1/D12) | ELISA | Mouse antibody |
| MRO-044LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (P4/D10) | ELISA | Mouse antibody |
| MRO-045LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (A47/B1) | ELISA | Mouse antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4220 | Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) | WB, ELISA | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-3316CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC01-8fH/10fL); Fab Fragment | Neut | Human Fab |
| MRO-3317CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC01-8fH/6fL); Fab Fragment | Neut | Human Fab |
| MRO-3318CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 3489_UA); Fab Fragment | Neut | Human Fab |
| MRO-3319CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone gVRC-H3dC38/VRC01L); Fab Fragment | ELISA, Neut | Human Fab |
| MRO-3320CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone gVRC-H4dC38/VRC01L); Fab Fragment | ELISA, Neut | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0201CQ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone S20); scFv Fragment | ELISA, Neut | Human scFv |
| FAMAB-0058WJ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone P20); scFv Fragment | ELISA, Neut | Human scFv |
| HPAB-0713-YJ-S(P) | Monkey Anti-gp120 Recombinant Antibody (GE331); scFv Fragment | ELISA, Neut | Monkey scFv |
| HPAB-0714-YJ-S(P) | Monkey Anti-gp120 Recombinant Antibody (GE443); scFv Fragment | ELISA | Monkey scFv |
| HPAB-0716-YJ-S(P) | Monkey Anti-gp120 Recombinant Antibody (2S1H3); scFv Fragment | ELISA, IHC | Monkey scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-101-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment | WB, ELISA, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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