Rabbit Anti-HIV-1 gp120 V3 Recombinant Antibody (clone 10A37) (CAT#: PABC-280)

This product is a recombinant Rabbit antibody that can recognize HIV-1 gp120 V3. 10A37 recognizes a peptide consisting of residues RIGPGQAFYATGDII (aa 308 to 324). 10A37, which has a better potency and breadth of neutralizing activity.


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Antagonist

Figure 1 Rabbit Anti-HIV-1 gp120 V3 Antibody (clone 10A37) in antagonist.

Figure 1 Rabbit Anti-HIV-1 gp120 V3 Antibody (clone 10A37) in antagonist.

Antibody competition against PGT121. Recombinant mAb 10A37 was used for the competition assay. Anti-gp41, recombinant mAb 2C2 was used as a negative control.

Qin, Y., Banerjee, S., Agrawal, A., Shi, H., Banasik, M., Lin, F., ... & Cho, M. W. (2015). Characterization of a large panel of rabbit monoclonal antibodies against HIV-1 gp120 and isolation of novel neutralizing antibodies against the V3 loop. PloS one, 10(6), e0128823.


Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • HIV-1 gp120 V3
  • Species Reactivity
  • HIV-1 group M subtype B
  • Clone
  • 10A37
  • Applications
  • ELISA, Neut

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120 V3 loop; gp120 V3 loop; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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