Rabbit Anti-HMGCS1 Recombinant Antibody (clone 2506W07) (CAT#: VS-0625-FY28)
This Rabbit IgG monoclonal antibody, clone 2506W07, broadly targets HMGCS1 in Human, Mouse, and Rat. Its immunogen is a recombinant Rat HMGCS1 fusion protein, with an epitope spanning amino acids 1-641. With an approximate antigen size of 45 kDa, this antibody is applicable in Immunohistochemistry (Paraffin), Immunoprecipitation, and Western Blot, offering versatile detection capabilities for HMGCS1.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Species Reactivity
- Human, Mouse, Rat
- Clone
- 2506W07
- Applications
- Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot
- Related Disease
- Congenital Myopathy 3 With Rigid Spine and Alcoholic Ketoacidosis
Product Property
- Purification
- Purified with Protein A or G affinity chromatography
- Purity
- >90% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 59% PBS, 40% glycerol (glycerin, glycerine), 0.05% BSA, pH 7.2-7.4
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Optimal dilutions for assays should be determined by the user.
Target
- Alternative Names
- 3-Hydroxy-3-Methylglutaryl-CoA Synthase 1; 3-Hydroxy-3-Methylglutaryl-Coenzyme A Synthase 1 (Soluble); 3-Hydroxy-3-Methylglutaryl Coenzyme A (HMG-CoA) Synthase; 3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble); EC 2.3.3.10; HMGCS; Hydroxymethylglutaryl-CoA Synthase, Cytoplasmic; 3-Hydroxy-3-Methylglutaryl Coenzyme A Synthase; HMG-CoA Synthase
- Gene ID
- 3157
- UniProt ID
- Q01581
- Long Name
- 3-Hydroxy-3-Methylglutaryl-CoA Synthase 1
- Sequence Similarities
- Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Ubiquitination at Lys46, Lys206, Lys273, Lys291, Lys317, Lys321, Lys330, Lys368, Lys400, Lys409, and Lys428
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen
- Protein Refseq
- XP_047273091.1; XP_054208462.1; NP_001091742.1; NP_001311148.1; NP_001311149.1
- Function
- Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for cholesterol synthesis.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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