This product is a recombinant antibody that recognizes HPAI. The monoclonal antibody 4F5 reacts with the epitope of HPAI.
Figure 1. Western blotting analysis of 4F5 scFv binding to denatured HA in reducing conditions.
Note that the 4F5 scFv clone binds with two protein species with molecular masses of about 70 kD and 43 kD, the H5N1 influenza A HA protein and its major subunit HA1, respectively.
Zhang, X., Qi, X., Zhang, Q., Zeng, X., Shi, Z., Jin, Q., ... & Jiao, Y. (2013). Human 4F5 single-chain Fv antibody recognizing a conserved HA1 epitope has broad neutralizing potency against H5N1 influenza A viruses of different clades. Antiviral research, 99(2), 91-99.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0800-FY-F(E) | Recombinant Anti-HPAI Antibody scFv Fragment (4F5) | N, E |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0800-FY-S(P) | Recombinant Anti-HPAI Antibody Fab Fragment (4F5) | N, E |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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