Mouse Anti-KMT2C Recombinant Antibody (VS3-FY2937) (CAT#: VS3-FY2937)
The anti-KMT2C product is a recombinant mouse monoclonal antibody that has a high affinity for human KMT2C protein. It cross-reacts with mouse species. The calculated molecular weight of the protein is about 541.4 kDa. The antibody can be utilized for detection of target protein by Western Blot (1/500-1/2000).
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/74736/1457_H5_6_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/74736/1457_H5_6_selected.jpg
Figure 2 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000055609-KMT2C
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000055609-KMT2C
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human and Mouse KMT2C
- Species Reactivity
- Human, Mouse
- Applications
- Western Blot
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 541.4 kDa.
- Related Disease
- Kleefstra Syndrome 2 and Kleefstra Syndrome Due To A Point Mutation
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Target
- Alternative Names
- Lysine Methyltransferase 2C; Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 3; Lysine (K)-Specific Methyltransferase 2C; Homologous To ALR Protein; MLL3; HALR; Histone-Lysine N-Methyltransferase, H3 Lysine-4 Specific; Myeloid/Lymphoid Or Mixed-Lineage Leukemia 3
- Gene ID
- 58508
- UniProt ID
- Q8NEZ4
- Sequence Similarities
- Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q8NEZ4)
Modification sites at neXtProt (NX_Q8NEZ4)
Glycosylation from GlyGen (Q8NEZ4) 13 sites, 1 O-linked glycan (13 sites)
- Function
- Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) (PubMed:25561738).
Part of chromatin remodeling machinery predominantly forms H3K4me1 methylation marks at active chromatin sites where transcription and DNA repair take place.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-4012z | Mouse Anti-KMT2C Recombinant Antibody (clone 43H10) | WB, ELISA | Mouse IgG1, κ |
| VS3-WK1067 | Mouse Anti-KMT2C Recombinant Antibody (VS3-WK1067) | WB | Mouse IgG1, κ |
| VS7-0425-WR241 | Mouse Anti-KMT2C Recombinant Antibody (clone 7D5D7) | FC | Mouse IgG1 |
| VS7-0425-WR242 | Mouse Anti-KMT2C Recombinant Antibody (clone 6D1B9) | IHC, ICC, FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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