Mouse Anti-MHC class II molecule Recombinant Antibody (clone 2G11) (CAT#: HPAB-0474-YJ)

This product is a recombinant mouse antibody that recognizes (both natural and recombinant) Avian MHC class II molecule. It may be useful for the treatment or prevention of various diseases in animals, such as avians, such as cancers and infectious diseases.


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  • Published Data
  • Datasheet
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  • COA
ELISA

Figure 1 The curve shows effective protein production and secretion of 2G11-vaccibody (absorbance at 450 nm) into the supernatant of transiently transfected HEK293E cells.

Figure 1 The curve shows effective protein production and secretion of 2G11-vaccibody (absorbance at 450 nm) into the supernatant of transiently transfected HEK293E cells.

FC

Figure 2 Flow cytometry analysis on binding to CD45+ chicken PBMC.

Figure 2 Flow cytometry analysis on binding to CD45+ chicken PBMC.

Isolated chicken PBMC were stained with 2G11 vaccibody and negative controls (Staining buffer, non-targeted aNIP control and isotype control). Binding analysis were performed on gated CD45+ cells using overlaying histograms.

FC

Figure 3 Flow cytometry analysis on binding to CD45+ chicken PBMC.

Figure 3 Flow cytometry analysis on binding to CD45+ chicken PBMC.

Isolated chicken PBMC were stained with the 2G11 mAb (AH Diagnostics) and negative controls (Staining buffer and isotype control). Binding analysis were performed on gated CD45+ cells using overlaying histograms. Purple filled: 2G11 mAb (positive control), Green: Staining Buffer, Pink: 2G11 mAb isotype control.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • Avian
  • Species Reactivity
  • Avian
  • Clone
  • 2G11
  • Applications
  • FC, Vaccibody
  • Related Disease
  • Cancers, Infectious diseases

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Flow Cytometry, Vaccibody.

Target

  • Alternative Names
  • MHC class II molecule

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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