Mouse Anti-N. meningitidis PS Recombinant Antibody (clone 3624.22) (CAT#: FAMAB-0102JF)
Recombinant mouse monoclonal antibody specially binds to Neisseria meningitidis group C PS (MCPS). This anti-PS antibody 3624.22 can be useful in the treatment of patients infected by encapsulated bacteria.
Specific Inquiry
FC
Figure 1 The number of CHP-134 cells (y axis) versus cellular fluorescence (x axis).
Approximate magnifications, ×57.
Shin, J. S., Lin, J. S., Anderson, P. W., Insel, R. A., & Nahm, M. H. (2001). Monoclonal antibodies specific for Neisseria meningitidis group B polysaccharide and their peptide mimotopes. Infection and immunity, 69(5), 3335-3342.
IHC
Figure 2 A cryosection of 10-day-old mouse brain (cerebellum) was stained with HmenB3.
Positive-staining cells have a brick-red color.
Shin, J. S., Lin, J. S., Anderson, P. W., Insel, R. A., & Nahm, M. H. (2001). Monoclonal antibodies specific for Neisseria meningitidis group B polysaccharide and their peptide mimotopes. Infection and immunity, 69(5), 3335-3342.
ELISA
Figure 3 The amount of bacteriophage bound (y axis) to the microwells coated with different MAbs versus various dilutions of phage clones (x axis).
Dilution (x axis) indicates fold dilutions, and the optical density (y axis) is expressed in milli-absorbance units.
Shin, J. S., Lin, J. S., Anderson, P. W., Insel, R. A., & Nahm, M. H. (2001). Monoclonal antibodies specific for Neisseria meningitidis group B polysaccharide and their peptide mimotopes. Infection and immunity, 69(5), 3335-3342.
Inhib
Figure 4 Inhibition of bacteriolysis active with human complement in a pooled serum collected at week 16 from monkeys.
Group B N. meningitidis 8765 (B:15:P1.3:L3,7) was used in the bactericidal assay.
Zollinger, W. D., Moran, E. E., Devi, S. J., & Frasch, C. E. (1997). Bactericidal antibody responses of juvenile rhesus monkeys immunized with group B Neisseria meningitidis capsular polysaccharide-protein conjugate vaccines. Infection and immunity, 65(3), 1053-1060.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgM, κ
- Specificity
- Neisseria meningitidis group C PS
- Clone
- 3624.22
- Applications
- ELISA, IHC, Inhib, FC
- Related Disease
- Neisseria meningitidis infection
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The N. meningitidis PS antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Immunohistochemistry, Inhibition, Flow Cytometry.
Target
- Alternative Names
- Capsular polysaccharide; PS
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0102JF-F(E) | Mouse Anti-N. meningitidis PS Recombinant Antibody (clone 3624.22); Fab Fragment | DB, FELISA, ELISA, FuncS | Mouse Fab |
| FAMAB-0103JF-F(E) | Mouse Anti-N. meningitidis PS Recombinant Antibody (clone 2055.5); Fab Fragment | DB, FELISA, ELISA, FuncS | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0102JF-S(P) | Mouse Anti-N. meningitidis PS Recombinant Antibody (clone 3624.22); scFv Fragment | DB, FELISA, ELISA, FuncS | Mouse scFv |
| FAMAB-0103JF-S(P) | Mouse Anti-N. meningitidis PS Recombinant Antibody (clone 2055.5); scFv Fragment | DB, FELISA, ELISA, FuncS | Mouse scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0103JF | Mouse Anti-N. meningitidis PS Recombinant Antibody (clone 2055.5) | ELISA, Inhib, FuncS | Mouse IgG3, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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