AbPlus™ Anti-PPIB Magnetic Beads (VS-0724-YC1427)
CAT#: VS-0724-YC1427
The AbPlus Anti-PPIB Magnetic Beads (VS-0724-YC1427) is an innovative affinity resin which is bound with anti-PPIB specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of PPIB protein under native and denaturing conditions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HUVEC TERT2
Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12720/1752_C1_2_cr5804bfa7d57a4_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11487/30837_B_9_5.jpg
Normal Tissue
Figure 3 Thyroid gland
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11487/30837_B_1_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells
Staining: Low
Intensity: Weak
Quantity:>75%
Enterocytes
Staining: Low
Intensity: Weak
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11487/30837_A_7_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11487/30837_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11487/30837_A_7_5.jpg
Normal Tissue
Figure 7 Testis
Sertoli cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11487/30837_A_6_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11487/30837_A_9_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166794-PPIB/subcellular
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-PPIB specific antibody
- Target
- PPIB
- Immunogen
- Synthetic peptide corresponding to the C-terminus of the human Cyclophilin B/PPIB.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression.
- Alternative Names
- OI9; CYPB; SCYLP; CYP-S1; HEL-S-39
- Gene ID
- 5479
- UniProt ID
- P23284
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CITATIONS
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "PPIB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2805 | Hi-Affi™ Recombinant Rabbit Anti-PPIB Monoclonal Antibody (DS2805AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0207J | Mouse Anti-PPIB Recombinant Antibody (clone 1B3) | WB, IHC-P, IF | Mouse IgG |
| ZG-0208J | Mouse Anti-PPIB Recombinant Antibody (clone 2B10) | IF, ICC, WB, IHC-P | Mouse IgG |
| ZG-0209J | Mouse Anti-PPIB Recombinant Antibody (clone 2B10), AbFluor 350 | IF, ICC, WB, IHC-P | Mouse IgG |
| ZG-0210J | Mouse Anti-PPIB Recombinant Antibody (clone 2B10), AbFluor 405 | IF, ICC, WB, IHC-P | Mouse IgG |
| ZG-0211J | Mouse Anti-PPIB Recombinant Antibody (clone 2B10), AbFluor 488 | IF, ICC, WB, IHC-P | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1709 | Anti-PPIB Immunohistochemistry Kit | IHC | |
| VS-0525-XY5596 | Anti-Human PPIB Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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