AbPlus™ Anti-RFXANK Magnetic Beads (VS-0724-YC554) (CAT#: VS-0724-YC554)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-RFXANK specific antibody

• Target
• RFXANK

• Immunogen
• Recombinant human RFXANK fragment derived from E. coli.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2013]

• Alternative Names
• Regulatory Factor X Associated Ankyrin Containing Protein; Regulatory Factor X Subunit B; Ankyrin Repeat-Containing Regulatory Factor X-Associated Protein; Regulatory Factor X-Associated Ankyrin-Containing Protein; Ankyrin Repeat Family A Protein 1; DNA-Binding Protein RFXANK; RFX-Bdelta4;

• Gene ID
• 8625

• UniProt ID
• O14593

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