Recombinant Mouse Anti-RV-B14 outer surface Antibody (C5) (CAT#: PABC-378)
This product is a recombinant Mouse antibody that can recognize RV-B14 outer surface. A neutralizing antibody, C5, binds to RV-B14 and causes significant structural rearrangements of the capsid to allow release of the viral genome. C5 can bind the neutralizing immunogenic (NIm)-III site on the RV-B14 outer surface.
Specific Inquiry
Neut
Figure 1 Mouse Anti-RV-B14 outer surface Antibody (C5) in Neut.
The C5 Fab binds to a threefold proximal region on RV-B14. The C5 Fab exhibits neutralizing activity against RV-B14 infection. The virus concentration used in the experiments was about 3 × 10 −8 nM, assuming a particle-to-plaque forming unit ratio of about 200 (62). Shown is a plot of percent inhibition as a function of the logarithm of the Fab concentration. Error bars indicate SDs.
Dong, Y., Liu, Y., Jiang, W., Smith, T. J., Xu, Z., & Rossmann, M. G. (2017). Antibody-induced uncoating of human rhinovirus B14. Proceedings of the National Academy of Sciences, 114(30), 8017-8022.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- RV-B14 outer surface
- Species Reactivity
- RV-B14
- Clone
- C5
- Applications
- ELISA, Neut
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
- Alternative Names
- RV-B14 outer surface; human rhinovirus B14 outer surface
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-378 | Recombinant Mouse Anti-RV-B14 outer surface Antibody Fab Fragment (C5) | ELISA, Neut | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-378 | Recombinant Mouse Anti-RV-B14 outer surface Antibody scFv Fragment (C5) | ELISA, Neut | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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