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    Mouse Anti-SCN3A Recombinant Antibody (clone 2506W0033) (CAT#: VS-0625-FY138)

    This monoclonal antibody targets Sodium Voltage-Gated Channel Alpha Subunit 3 (SCN3A), a member of the voltage-gated sodium channel family. SCN3A is widely expressed and involved in the generation and propagation of action potentials. The antibody, produced in mice and reactive with human samples, is applicable in ELISA, enabling researchers to investigate SCN3A's function in neuronal signaling and disease.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 IHC staining of human caudate
    Figure 1 IHC staining of human caudate
    (Immunohistochemical staining of human caudate shows strong cytoplasmic positivity in neurons.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/35396/ihc_selected.jpg
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/35396/73252_B_9_5.jpg
    Figure 3 Cerebellum
    Figure 3 Cerebellum
    (Cells in granular layer Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in molecular layer Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/35396/73252_B_7_8.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/35396/73252_A_8_3.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Cholangiocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/35396/73252_A_8_4.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/35396/73252_A_8_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Pachytene spermatocytes Staining: Low Intensity: Weak Quantity:>75% Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Moderate)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/35396/73252_A_4_6.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enhanced (JURKAT, Karpas-707, MOLT-4, RPTEC TERT1, SH-SY5Y)
    Figure 8 RNA cell line category: Cell line enhanced (JURKAT, Karpas-707, MOLT-4, RPTEC TERT1, SH-SY5Y)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000153253-SCN3A

    Specifications

    • Immunogen
    • Human SCN3A
    • Host Species
    • Mouse
    • Type
    • Mouse IgG
    • Specificity
    • The antibody specifically recognizes the peptide of the Human SCN3A.
    • Species Reactivity
    • Human
    • Clone
    • 2506W0033
    • Applications
    • ELISA

    Product Property

    • Purification
    • Purified with Protein A or G affinity chromatography
    • Purity
    • >90% as determined by SDS-PAGE
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • The buffer commonly used is typically composed of 1 M Tris-HCl and 100 mM glycine. For more detailed information, refer to the Certificate of Analysis (COA).
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • ELISA: 1:1000-1:3000
      Other applications are under development. Optimal dilutions for assays should be determined by the user.

    Target

    • Alternative Names
    • Sodium Voltage-Gated Channel Alpha Subunit 3; Sodium Channel, Voltage-Gated, Type III, Alpha Polypeptide; Sodium Channel, Voltage Gated, Type III Alpha Subunit; Voltage-Gated Sodium Channel Subunit Alpha Nav1.3; Sodium Channel Protein Brain III Subunit Alpha; Sodium Channel Protein Type III Subunit Alpha; Voltage-Gated Sodium Channel Subtype III
    • Long Name
    • Sodium channel protein type 3 subunit alpha

    Recommended Products

    Secondary Antibody

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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