Mouse Anti-Tn antigen Recombinant Antibody (clone 83D4)
CAT#: FAMAB-0311JF
Recombinant monoclonal antibody strongly binds to the Tn determinant (GalNAca-O-Ser/Thr) expressed in 90% of breast, ovary, and colon carcinomas. 83D4 is a mouse monoclonal antibody that can be useful as a immunohistochemical marker on paraffin embedded tissues.
Specifications
- Immunogen
- An invasive human breast carcinoma
- Host Species
- Mouse
- Type
- Mouse IgM, κ
- Specificity
- Human Tn antigen
- Species Reactivity
- Human
- Clone
- 83D4
- Applications
- IB, IF, ELISA, FuncS
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Tn antigen
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High Sensitivity and Consistency
We have found the clone 83D4 antibody to be highly sensitive, allowing us to identify Tn antigens with great precision. Its consistency across experiments ensures that our results are reproducible and valid, enhancing our confidence in the data.
Versatile Experimental Use
This antibody's versatility allows us to use it across various applications such as ELISA and Immunofluorescence, providing comprehensive insights into cancer cell behavior and marker expression, which is crucial for our exploratory studies.
Q&As
-
What makes the Tn antigen a significant target in cancer research?
A: The Tn antigen is a carbohydrate alteration found on the surface of cancer cells, making it a key marker for tumor identification and a potential target for therapeutic interventions. Studying this antigen can provide insights into cancer cell biology and the development of targeted treatments.
-
What are the specific applications of this antibody?
A: The clone 83D4 antibody is well-suited for use in Immunoblotting (IB), Immunofluorescence (IF), ELISA, and Functional Studies (FuncS). Its specificity for the Tn determinant makes it an excellent tool for detailed cancer research and analysis.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Clone 83D4"
- CAT
- Product Name
See other products for "Tn antigen"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-980 | Recombinant Anti-Tn antigen Antibody | ELISA, WB, FuncS | IgG |
| MHH-980 | Recombinant Human Anti-Tn antigen Antibody | IF, WB, FuncS | IgG |
| MOB-030CQ | Mouse Anti-Tn Antigen Recombinant Antibody (clone YC145) | WB, IF, IHC | Mouse IgM, κ |
| FAMAB-1419CQ | Human Anti-Tn antigen Recombinant Antibody (clone 237) | WB, ELISA | Human IgG1 |
| VS2-QX26 | Mouse Anti-Tn antigen Recombinant Antibody (clone BRIC 111) | FuncS | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-980-F(E) | Recombinant Anti-Tn antigen Antibody Fab Fragment | Neut, IF, FuncS | Fab |
| MHH-980-F(E) | Recombinant Human Anti-Tn antigen Antibody Fab Fragment | WB, IP, FuncS | Fab |
| HPAB-0319CQ-F(E) | Mouse Anti-Tn Antigen Recombinant Antibody (clone MLS128); Fab Fragment | WB, IHC, DB, FC, Inhib | Mouse Fab |
| FAMAB-0311JF-F(E) | Mouse Anti-Tn antigen Recombinant Antibody (clone 83D4); Fab Fragment | IB, IF, ELISA, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-980-S(P) | Recombinant Anti-Tn antigen Antibody scFv Fragment | IF, FC, Biosensors, FuncS | scFv |
| MHH-980-S(P) | Recombinant Human Anti-Tn antigen Antibody scFv Fragment | WB, IF, FuncS | scFv |
| FAMAB-0311JF-S(P) | Mouse Anti-Tn antigen Recombinant Antibody (clone 83D4); scFv Fragment | IB, IF, ELISA, FuncS | Mouse scFv |
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