Mouse Anti-TRIM29 Recombinant Antibody (clone 8C8G5) (CAT#: VS7-0425-WR1050)
This product is a mouse IgG2a antibody that binds to human TRIM29. The antibody 8C8G5 recognizes specific amino acid domain of human TRIM29 (AA: 451-588). It can be used for WB, ICC, and FC assays.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SiHa
(Immunofluorescent staining of human cell line SiHa shows localization to intermediate filaments.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20053/if_selected.jpg
(Immunofluorescent staining of human cell line SiHa shows localization to intermediate filaments.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20053/if_selected.jpg
Figure 2 Esophagus
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20053/46556_B_4_1_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20053/46556_B_4_1_val_selected.jpg
Figure 3 IHC staining of human spleen
(Immunohistochemical staining of human spleen shows strong nuclear and cytoplasmic positivity in cells in red pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74841/169666_B_9_4_selected.jpg
(Immunohistochemical staining of human spleen shows strong nuclear and cytoplasmic positivity in cells in red pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74841/169666_B_9_4_selected.jpg
Figure 4 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20053/46556_B_9_5.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20053/46556_B_9_5.jpg
Figure 5 Skin
(Cells in basal layer Staining: High Intensity: Strong Quantity:>75% Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Cells in spinous layer Staining: High Intensity: Strong Quantity:>75% Langerhans cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20053/46556_B_8_1.jpg
(Cells in basal layer Staining: High Intensity: Strong Quantity:>75% Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Cells in spinous layer Staining: High Intensity: Strong Quantity:>75% Langerhans cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20053/46556_B_8_1.jpg
Figure 6 RNA cell line category: Cell line enhanced (HaCaT, HBEC3-KT, hTCEpi, RT4, SiHa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000137699-TRIM29
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000137699-TRIM29
Specifications
- Immunogen
- Recombinant human TRIM29 (AA: 451-588) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human TRIM29
- Species Reactivity
- Human
- Clone
- 8C8G5
- Molecule Class
- Trim Protein
- Applications
- WB, ICC, FC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunocytochemistry: 1:100 - 1:500
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- TRIM29; Tripartite Motif Containing 29; Tripartite Motif-Containing 29; Ataxia-Telangiectasia Group D-Associated Protein; Tripartite Motif-Containing Protein 29; ATDC; Tripartite Motif Protein TRIM29; Ataxia Telangiectasia Group D-Associated Protein
- Gene ID
- 23650
- UniProt ID
- Q14134
- Long Name
- Tripartite Motif Containing 29
- Cellular Localization
- Cytoplasm; Lysosome
- Post Translation Modifications
- Phosphoprotein
- Protein Refseq
- NP_001317311.1
- Function
- Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation.
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TRIM29"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Rabbit Monoclonal Antibody Products
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3462z | Mouse Anti-TRIM29 Recombinant Antibody (clone 22D5) | WB, IP, IF, ELISA | Mouse IgG1, κ |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS7-0425-WR1050. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: ELISA, IHC
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: FC, IHC, FuncS, Inhib, Cyt
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: SPR, Inhib, FuncS
Application: Neut, ELISA, WB, SPR, IF, EM
-3.jpg)
Application: IB, FC, ELISA, FuncS
Application: EM, ELISA, ICC, IHC-Fr, IHC-P, WB
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
