B*07:02/Influenza A virus (H1N1) Nucleocapsid protein (TYQRTRALV) MHC Pentamer (CAT#: MHC-YC206)
MHC multimers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a Pentamer of peptide/MHC complex with IAV-derived peptide of TYQRTRALV sequence covering 147-155 and B*07:02 molecule. The peptide/MHC pentamer provided here is unlabeled or fluorescent labeled such as Biotin, R-PE, APC. And all of them are available in 50, 150 or 500 tests.
Specific Inquiry
Specifications
- Allele
- B*07:02
- Class
- Class I
- Antigen
- Influenza A virus (H1N1) Nucleocapsid protein
- Antigen Species
- IAV
- Peptide
- TYQRTRALV
- Range
- 147-155
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway. Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
- Alternative Names
- FLUAVs5gp1
- Gene ID
- 956531
- UniProt ID
- P03466
Downloads
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Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-096 | Recombinant Anti-IAV NP VHH Single Domain Antibody | IHC, FC, CA, FuncS | Llama VHH |
| NBD-0050-YJ-VHH | Camelid Anti-IAV NP Recombinant Single Domain Antibody (Np1) | ELISA | Camelid VHH |
| NBD-0051-YJ-VHH | Camelid Anti-IAV NP Recombinant Single Domain Antibody (Np54) | ELISA | Camelid VHH |
| NBD-0052-YJ-VHH | Camelid Anti-IAV NP Recombinant Single Domain Antibody (Np135) | ELISA | Camelid VHH |
| NBD-0053-YJ-VHH | Camelid Anti-IAV NP Recombinant Single Domain Antibody (Np170) | ELISA | Camelid VHH |
Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B040(A) | Recombinant Anti-IAV NP Intrabody [(D-Arg)9] | WB, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B040(G) | Recombinant Anti-IAV NP Intrabody [+36 GFP] | WB, ICC, Neut, FuncS | scFv-(+36GFP) |
| IAB-B040(T) | Recombinant Anti-IAV NP Intrabody [Tat] | IF, FC, FuncS | scFv-Tat |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2144CQ | Recombinant Mouse Anti-IAV NP Antibody (J320) | ELISA, IF, LFIA | Mouse antibody |
| MOB-Z010-YC | Mouse Anti-IAV NP Recombinant Antibody (clone DEC.YC010) | ELISA, IP, WB, IF, Bilateral Flow | Mouse IgG1 |
| MOB-Z011-YC | Mouse Anti-IAV NP Recombinant Antibody (clone DEC.YC011) | ELISA, IP, WB, IF | Mouse IgG1 |
| FAMAB-1804CQ | Human Anti-IAV NP Recombinant Antibody (clone 2-8C) | Neut, WB, ELISA, IF, IHC | Human IgG1 |
| VS-0923-FY96 | Recombinant Mouse Anti-IAV NP Antibody (VS-0923-FY96) | ELISA, WB | Mouse IgG1 |
MHC Tetramer for Virology
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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