Recombinant Human Anti-DCHS1 Soluble TCR (LA12) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF1612)
Human TCR (LA12) recognizes DCHS1 peptide (TLFTIVGTV) in the context of HLA-A2. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (LA12). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HUVEC TERT2
(Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/1752_B1_18_cr5804bf34eb55b_selected.jpg
(Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/1752_B1_18_cr5804bf34eb55b_selected.jpg
Figure 2 IHC staining of human esophagus
(Immunohistochemical staining of human esophagus shows strong cytoplasmic and nucleolar positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/ihc_selected.jpg
(Immunohistochemical staining of human esophagus shows strong cytoplasmic and nucleolar positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/ihc_selected.jpg
Figure 3 IHC staining of human rectum
(Immunohistochemical staining of human rectum shows strong cytoplasmic positivity in granular pattern in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_6_3_selected.jpg
(Immunohistochemical staining of human rectum shows strong cytoplasmic positivity in granular pattern in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_6_3_selected.jpg
Figure 4 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_B_9_5.jpg
(Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_B_9_5.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_9_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_9_4.jpg
Figure 6 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_7_5.jpg
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_7_5.jpg
Figure 7 Endometrium
(Cells in endometrial stroma Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/109028_B_4_3.jpg
(Cells in endometrial stroma Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/109028_B_4_3.jpg
Figure 8 RNA cell line category: Cell line enhanced (AF22, HUVEC TERT2, REH, SH-SY5Y, TIME)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166341-DCHS1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166341-DCHS1
Specifications
- Host Species
- Human
- Target
- DCHS1
- Species Reactivity
- Human
- Epitope
- TLFTIVGTV
- MHC
- HLA-A2
- Clone
- LA12
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- Dachsous Cadherin-Related 1; Cadherin-Related Family Member 6; Protein Dachsous Homolog 1; Cadherin-19; Cadherin-25; PCDH16; CDH25; CDH19; FIB1; Fibroblast Cadherin FIB1;
- Gene ID
- 8642
- UniProt ID
- Q96JQ0
Downloads
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Human Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1429CL-S(P) | Anti-Human DCHS1 Recombinant Antibody scFv Fragment | ELISA, WB | Fully human antibody |
| TAB-1429CL-F(E) | Anti-Human DCHS1 Recombinant Antibody Fab Fragment | ELISA, WB | Fully human antibody |
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